Suppression of voluntary ethanol intake in mice under constant light and constant darkness
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چکیده
منابع مشابه
Light and electron microscopic examination of pineal gland in rats exposed to constant light and constant darkness.
OBJECTIVE This study was aimed to examine the pineal gland of rats exposed to constant light and darkness at light and electron microscopic level. DESIGN For this purpose 18 male Wistar rats were used. Animals were divided into three groups. Rats in group I (Control) were kept under 12 hrs light: 12 hrs dark conditions. Rats in group II were exposed to constant darkness, while rats in group I...
متن کاملStrong resetting of the mammalian clock by constant light followed by constant darkness.
The mammalian molecular circadian clock in the suprachiasmatic nuclei (SCN) regulates locomotor activity rhythms as well as clocks in peripheral tissues (Reppert and Weaver, 2002; Ko and Takahashi, 2006). Constant light (LL) can induce behavioral and physiological arrhythmicity by desynchronizing clock cells in the SCN (Ohta et al., 2005). We examined how the disordered clock cells resynchroniz...
متن کاملPostnatal Constant Light Compensates Cryptochrome1 and 2 Double Deficiency for Disruption of Circadian Behavioral Rhythms in Mice under Constant Dark
Clock genes Cryptochrome (Cry1) and Cry2 are essential for expression of circadian rhythms in mice under constant darkness (DD). However, circadian rhythms in clock gene Per1 expression or clock protein PER2 are detected in the cultured suprachiasmatic nucleus (SCN) of neonatal Cry1 and Cry2 double deficient (Cry1 (-/-)/Cry2 (-/-)) mice. A lack of circadian rhythms in adult Cry1 (-/-)/Cry2 (-/-...
متن کاملInfluence of N-Phthaloyl GABA on the Circadian Rhythms of Lipid Peroxidation and Antioxidants in Wistar Rats under Constant Light
N-Phthaloyl GABA was administrated daily (50 mg/Kg body weight-i.p) to Wistar rats for 21 days and circadian rhythms of thiobarbituric acid reactive substances (TBARS) and antioxidants such as reduced glutathione (GSH), catalase (CAT) and superoxide dismutase (SOD) were studied under constant light (LL) conditions. Delayed acrophase of TBARS and advanced acrophase of antioxidants (GSH, CAT and ...
متن کاملConstant darkness is a mammalian biological signal.
Environmental light is a potent modulator of mammalian circadian rhythm and expression of clock genes. Constant darkness (DD) is regarded as a "free-running" circadian state. In nature, hibernating mammals encounter constant darkness (DD) seasonally. Circadian expression of enzymes involved in fat catabolism, procolipase (CLP) and pancreatic-lipase-related protein 2 (PLRP2), were identified in ...
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ژورنال
عنوان ژورنال: Alcohol
سال: 2020
ISSN: 0741-8329
DOI: 10.1016/j.alcohol.2019.05.009